Alya, developed by the team of Mariano Vazquez and Guillaume Houzeaux at the Barcelona Supercomputing Centre, performs cardiac electro-mechanics simulations, from tissue to organ level. The simulation involves the solution of multiscale model using a FEM-based electro-mechanical coupling solver, specifically optimised for the efficient use of supercomputing resources. Alya is available for use to research users on MareNostrum, ARCHER, and Cartesius; for clinical and industrial users, BSC recommends users access it as a service, due to the complexity involved with setting up simulations. To this purpose BSC is setting up a spin-off (ELEM Biotech) that will provide commercial software-as-a-service to biomedical industries based on Alya.
| Use scenario
Non-clinical research; Clinical research; Clinical decision support; Design & optimisation for medical devices; In silico clinical trial.
- Alya official website
- Alya documentation
- HPC Multi-scale computational modelling using Alya Red
- CompBioMed Webinar: HPC simulations of cardiac electrophysiology using patient specific models of the heart (using CHASTE and Alya)
- Alya Red: A Computational heart
- CompBioMed Virtual Humans Film
- Vázquez, M., Houzeaux, G., Koric, S., Artigues, A., Aguado-Sierra, J., Arís, R., … & Taha, A. (2016). Alya: Multiphysics engineering simulation toward exascale. Journal of Computational Science, 14, 15-27.
- Calmet, H., Kleinstreuer, C., Houzeaux, G., Kolanjiyil, A. V., Lehmkuhl, O., Olivares, E., & Vázquez, M. (2018). Subject-variability effects on micron particle deposition in human nasal cavities. Journal of Aerosol Science, 115, 12-28.
- Lafortune, P., Arís, R., Vázquez, M., & Houzeaux, G. (2012). Coupled electromechanical model of the heart: parallel finite element formulation. International journal for numerical methods in biomedical engineering, 28(1), 72-86.