Computer Tomography to Strength (CT2S) is an on-line service developed by the team of Prof Marco Viceconti at the Insigneo Institute at the University of Sheffield (UK), which allows the prediction of the biomechanical strength of a patient’s bone from a clinical CT scan of that bone. The service operates by creating a patient-specific finite element model of the bone, using a state of the art image-processing pipeline. This very precise model of the patient’s anatomy is then examined under a range of highly realistic simulated loading conditions, including walking, running, stair-climbing and falling, and the fracture load is computed in each case. Data summarising the identified fracture strength is returned to the user. The solution is currently exposed as a service, accessible through a web interface; the backend HPC system currently in use is USFD’s own ShARC. The service is currently provided at cost, with a significant discount for non-sponsored clinical studies. USFD is currently exploring the best marketing strategy.
Clinical research, Clinical decision support, In silico clinical trial.
Do uncertainty quantification; Multiscale model.
- CT2S official website
- Predicting the risk of fall – A computational modelling approach using CT2S
- CompBioMed Virtual Humans Film