Virtual Assay

Application description

Virtual Assay is used to perform simulations of drug effects in populations of human ventricular cells, and to predict potential side effects of the drugs on the human heart. Virtual Assay has been designed to be accessible by everyone, including people with little or no expertise in computer modelling and simulations. The target users are mainly pharmaceutical companies and academia. In industry, the main application would be for drug safety testing during pre-clinical drug development. In academia, it can be used both for research and teaching. Virtual Assay is licenced through Oxford University Innovation.

A free academic licence and a commercial licence are available, and they can be requested at:


Technical specifications 

Virtual Assay is not a fully integrated HPC application and can run on most modern 64-bit PCs and laptops. The software can be installed only on Windows machines (or virtual machines) at present. The software provides a framework where in a population, drug simulations are performed, analysed and stored independently for each model, and this facilitates parallelisation. The software is set to automatically run simulations in parallel, up to the number of cores available.

The code is mainly written in C++ and the following is the minimum recommended hardware specification:

  • Intel i7 quad-core processor or AMD equivalent
  • 8 GB RAM
  • 5 GB hard disk space

Clinical Use:

In Silico Trials

License type:

Custom license, free download for Academic use

User Resources

Related articles

  • Passini E et al. 2017, Human in silico drug trials demonstrate higher accuracy than animal models in predicting clinical pro-arrhythmic cardiotoxicity. DOI
  • Britton O et al. 2013, Experimentally−calibrated population of models predicts and explains inter−subject variability in cardiac cellular electrophysiology. DOI
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