openBF is an open-source 1D blood flow solver based on MUSCL finite-volume numerical scheme, written in Julia and released under Apache 2.0 free software license. The software is developed by Alessandro Melis and Alberto Marzo at the Insigneo Institute at the university of Sheffield (UK).
openBF has been used for modelling pathologies of the cardiovascular system such as vasospasm and ischaemic stroke. It has also been used for modelling mechanical thrombectomy procedures and support the development of next-generation thrombectomy devices together with Anaconda, a Spanish SME.
Available for academic and clinical researchers, the code is Distributed open-source through Github. Information and documentation on the code are available on Github. Users can download the code from the Gihub repository and install it on their local machines/HPC clusters. The code is deployed on ShARC, USFD’s HPC cluster, but external users need a guest account to access it.
HPC usage and parallel performance
- PhD Thesis: Gaussian process emulators for 1D vascular models. Link
- Melis A. et al. 2017, Bayesian sensitivity analysis of a 1D vascular model with Gaussian process emulators. DOI
- Melis A. et al. 2019, Improved biomechanical metrics of cerebral vasospasm identified via sensitivity analysis of a 1D cerebral circulation model. DOI