Author Archives: Nick Laver

The World’s Fastest Computer to Join Fight Against COVID-19

In our previous blog posts we have highlighted in the work of the Argonne National Laboratory (ANL) and Barcelona Supercomputing Center (BSC) that High Performance Computing (HPC) resources are an invaluable research tool. Much like their counterparts and colleagues around the world, Japan’s top scientists are now refocusing and accelerating their research efforts towards addressing…

AI-driven integrative biology for accelerating therapeutic drug discoveries to treat SARS-CoV-2

CompBioMed partners and academics from other research facilities are carrying out research to address the fundamental biological mechanisms of both the SARS-CoV-2 novel corona virus and the COVID-19 disease it causes. The ongoing research also includes an attempt to target the entire viral proteome (entire complement of proteins that is or can be expressed by…

Cardiotoxicity: Supercomputer-based in silico studies by CompBioMed Core Partners aiming to make COVID-19 treatment safer for the heart

The use of certain drugs can disturb the rhythm at which hearts beat.  This disruption can have toxic effects on the heart, which are particularly dangerous for those with underlying medical conditions.  Two drugs which are known to have proarrhythmic effects are the antimalarial drugs azithromycin and hydroxychloroquine. Azithromycin and hydroxychloroquine are thought to be…

Coronavirus Resources Across CompBioMed

Here at CoronaBlog, where we will be providing regular news and updates on the research activities of the CompBioMed members, their collaborators, and the wider scientific community, we have established several other resources to provide information and aid in the COVID-19 research efforts: CompBioMed and Coronavirus provides an overview of the current CompBioMed activities, highlighting the…

Webinar on how AI in Computational Medicine is Leading The Charge in COVID-19 Drug Discovery

There are tens, perhaps hundreds of billions of compounds which can be utilised by the pharmaceutical industry in the development of new drugs.  An exhaustive exploration of more than a handful experimentally is impossible, modern computational techniques are however now beginning to lead the way.  Quantum Chemical calculations run on High Performance Computers (HPCs) allow…